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糖皮质激素在治疗儿童重症肺炎支原体肺炎(MPP)中的价值

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2022年4月17日发(作者:肾药)

复里亏搪(医学版) 

180 Fudan Univ J Med Sci 

糖皮质激素在治疗儿童重症肺炎支原体 

肺炎(MPP)中的价值 

丁圣月4 王 建 王亚亭 丁俊丽 

(安徽医科大学第一附属医院儿科合肥230022) 

【摘要】 目的探讨糖皮质激素在儿童重症肺炎支原体肺炎治疗中的作用。方法 采用明胶颗粒凝聚法检测 

治疗组35例患儿 

血MP—IgM,对MP—IgM≥1:80且符合重症肺炎支原体肺炎临床诊断标准的53例患儿,依据是否使用糖皮质激 

素分成治疗组35例、对照组18例,比较两组之间临床症状、住院时间和并发症差异。结果

临床症状消失快、住院时间缩短、并发症少。结论

由此对机体的损害,改善预后。 

糖皮质激素可明显抑制重症肺炎支原体肺炎炎症反应,减轻 

【关键词】肺炎支原体肺炎(MPP); 重症; 儿童; 糖皮质激素 

【中图分类号】R 725.6 【文献标志码】A doi:10.3969/j.issn.1672—8467.2012.02.叭4 

The value of gluc0c0rtic0id in the therapy of children severe 

Mycoplasma pneumoniae pneumonia(MPP) 

DING Sheng—gangA,WANG Jian,WANG Ya—ring,DING J un—li 

0Department o/Pediatrics,the First Affiliated Hospital o{Anhui Medical University,He} 230022,Anhui Provim e China1 

[Abstract]0bjective To probe the therapeutic effects of g1ucocorticoids on severe Mycoplasma 

Methods Serum IgM titers for M.pneumoniae(MP)were pneumoniae pneumonia(MPP). 

determined by the gelatin particles condensed method.Fifty-three children whose serum MP—IgM≥ 

1:80 were recruited into our study.A1l subjects met the clinical diagnosis standards for severe MPP, 

and were divided into glucocorticoid treatment group(35 cases)and control group(1 8 cases).The 

clinical symptoms,hospitalization time and complications were documented. Results Compared 

with the control group,clinical symptoms of treatment group disappeared more quickly,accompanied 

with shorter hospitalization and 1ess complications. Conclusions Glucocorticoid can significantly 

inhibit the inflammatory response of severe MPP。alleviate the damage to the body by mycoplasma 

pneumoniae infection and improve the prognosis of severe MPP. 

[Key words]Mycoplasrna pneumoniae pneumonia(MPP); severe; children;prednisolone 

肺炎支原体(mycoplasma pneumoniae,MP)是 

我国儿童社区获得性肺炎(community acquited 

占流行年份儿童CAP病原的4() ~6() 。 

自2()10年春季来,我院门诊及病房收治的肺炎 

支原体肺炎(MP pneumonia,MPP)明显增加,文献 pneumonia,CAP)的常见病原菌之一,据报道 其 

△Corresponding author E—mail:dsg531 2@163.coin 

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